2HBH

Crystal structure of Vitamin D nuclear receptor ligand binding domain bound to a locked side-chain analog of calcitriol and SRC-1 peptide

2HBH の概要

関連するPDBエントリー1DB1 2HC4 2HCD
分子名称Vitamin D receptor, SRC-1 from Nuclear receptor coactivator 1, 1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z), ... (4 entities in total)
機能のキーワードalpha helical sandwich, gene regulation
由来する生物種Danio rerio (zebrafish)
詳細
細胞内の位置Nucleus Q9PTN2
Nucleus (By similarity) Q15788
ポリマー鎖数2
分子量合計36231.29
構造登録者
Rochel, N.,Hourai, S.,Moras, D. (登録日: 2006-06-14, 公開日: 2007-05-01, 最終更新日: 2011-07-13)
主引用文献
Rochel, N.,Hourai, S.,Perez-Garcia, X.,Rumbo, A.,Mourino, A.,Moras, D.
Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol
Arch.Biochem.Biophys., 460:172-176, 2007
PubMed: 17346665 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.abb.2007.01.031
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.65 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.254130.4%5.3%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード