2HBH

Crystal structure of Vitamin D nuclear receptor ligand binding domain bound to a locked side-chain analog of calcitriol and SRC-1 peptide

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
AVitamin D receptorpolymer30234060.71
UniProt (Q9PTN2)
Pfam (PF00104)
Danio rerio (zebrafish)@PDBj
BSRC-1 from Nuclear receptor coactivator 1polymer151776.11
UniProt (Q15788)
NCoA-1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, NY-REN-52 antigen
1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)non-polymer394.51
waterwater18.074

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains2
Total molecular weight35836.7
Non-Polymers*Number of molecules1
Total molecular weight394.5
All*Total molecular weight36231.3
*Water molecules are not included.