2HAR
Crystal structure of VDR LBD in complex with 2 alpha-(3-hydroxy-1-propoxy) calcitriol
Summary for 2HAR
Entry DOI | 10.2210/pdb2har/pdb |
Related | 1DB1 1IE8 1IE9 1S0Z 1S19 1TXI 2HAM 2HAS 2HB7 2HB8 |
Descriptor | Vitamin D3 receptor, 2ALPHA-(3-HYDROXYPROPOXY)-1ALPHA,25-DIHYDROXYVITAMIN D3 (3 entities in total) |
Functional Keywords | alpha helical sandwich, gene regulation |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P11473 |
Total number of polymer chains | 1 |
Total formula weight | 30296.06 |
Authors | Hourai, S.,Rochel, N.,Moras, D. (deposition date: 2006-06-13, release date: 2006-08-29, Last modification date: 2023-10-25) |
Primary citation | Hourai, S.,Fujishima, T.,Kittaka, A.,Suhara, Y.,Takayama, H.,Rochel, N.,Moras, D. Probing a Water Channel near the A-Ring of Receptor-Bound 1alpha,25-Dihydroxyvitamin D3 with Selected 2alpha-Substituted Analogues J.Med.Chem., 49:5199-5205, 2006 Cited by PubMed: 16913708DOI: 10.1021/jm0604070 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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