2HAR
Crystal structure of VDR LBD in complex with 2 alpha-(3-hydroxy-1-propoxy) calcitriol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vitamin D3 receptor | polymer | 263 | 29805.3 | 1 | UniProt (P11473) Pfam (PF00104) | Homo sapiens (human) | Vitamin D nuclear receptor, VDR, 1,25-dihydroxyvitamin D3 receptor |
| 2 | B (A) | 2ALPHA-(3-HYDROXYPROPOXY)-1ALPHA,25-DIHYDROXYVITAMIN D3 | non-polymer | 490.7 | 1 | Chemie (OCC) PubChem (23650432) PubChem (177600185) PubChem (25195037) PubChem (53826110) PubChem (56670920) PubChem (44296776) PubChem (58107369) PubChem (58893148) PubChem (45378770) PubChem (72750241) PubChem (73946579) PubChem (73946701) PubChem (87693878) PubChem (88121385) PubChem (88186894) PubChem (89734572) PubChem (90797856) PubChem (128495) PubChem (87490920) PubChem (88405378) PubChem (88426745) PubChem (90984811) PubChem (91369432) PubChem (90781843) PubChem (91355079) PubChem (91884895) PubChem (91799043) PubChem (102156050) PubChem (121290070) PubChem (9891771) PubChem (6438982) PubChem (129460345) PubChem (129539548) PubChem (129606921) PubChem (11205299) PubChem (6918141) PubChem (99945879) PubChem (101444867) PubChem (118571043) PubChem (9547582) PubChem (10228245) PubChem (10435690) PubChem (124003935) PubChem (11363854) PubChem (12018084) PubChem (12020391) PubChem (16062331) PubChem (126843179) PubChem (171318229) PubChem (171378604) PubChem (129460346) PubChem (129539545) PubChem (129539546) PubChem (129539547) PubChem (130344021) PubChem (131632592) PubChem (134692791) PubChem (140945261) PubChem (145705672) PubChem (147596026) PubChem (154723853) PubChem (155720925) PubChem (156599225) PubChem (158186496) PubChem (162489853) PubChem (162818586) PubChem (171122345) PubChem (171338414) | |||
| 3 | C (A) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 118 - 164 (UniProt: P11473)
A: 216 - 427 (UniProt: P11473)
| PDB | External Database | Details |
|---|---|---|
| Gly 114 | - | cloning artifact |
| Ser 115 | - | cloning artifact |
| His 116 | - | cloning artifact |
| Met 117 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29805.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 490.7 | |
| All* | Total formula weight | 30296.1 |
