2HAH
The structure of FIV 12S protease in complex with TL-3
Summary for 2HAH
Entry DOI | 10.2210/pdb2hah/pdb |
Related | 2AZ8 5FIV |
Related PRD ID | PRD_000434 |
Descriptor | Protease, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate (3 entities in total) |
Functional Keywords | retroviral, protease, aspartyl, feline, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Feline immunodeficiency virus (isolate Petaluma) |
Total number of polymer chains | 1 |
Total formula weight | 14135.30 |
Authors | Heaslet, H.,Lin, Y.C.,Elder, J.H.,Stout, C.D. (deposition date: 2006-06-12, release date: 2007-02-13, Last modification date: 2023-08-30) |
Primary citation | Heaslet, H.,Lin, Y.C.,Tam, K.,Torbett, B.E.,Elder, J.H.,Stout, C.D. Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3. Retrovirology, 4:1-1, 2007 Cited by PubMed: 17212810DOI: 10.1186/1742-4690-4-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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