2H9V
Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632
Summary for 2H9V
Entry DOI | 10.2210/pdb2h9v/pdb |
Related | 2F2U |
Descriptor | Rho-associated protein kinase 2, (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE (3 entities in total) |
Functional Keywords | protein kinase-inhibitor complex, transferase |
Biological source | Bos taurus (cattle) |
Cellular location | Cytoplasm: Q28021 |
Total number of polymer chains | 1 |
Total formula weight | 46023.36 |
Authors | Yamaguchi, H.,Miwa, Y.,Kasa, M.,Kitano, K.,Amano, M.,Kaibuchi, K.,Hakoshima, T. (deposition date: 2006-06-12, release date: 2006-12-05, Last modification date: 2024-03-13) |
Primary citation | Yamaguchi, H.,Miwa, Y.,Kasa, M.,Kitano, K.,Amano, M.,Kaibuchi, K.,Hakoshima, T. Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632 J.Biochem.(Tokyo), 140:305-311, 2006 Cited by PubMed: 16891330DOI: 10.1093/jb/mvj172 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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