2H9E

Crystal Structure of FXa/selectide/NAPC2 ternary complex

Summary for 2H9E

Entry DOI	10.2210/pdb2h9e/pdb
Descriptor	Coagulation factor X heavy chain, Coagulation factor X light chain, Anti-coagulant protein C2, ... (8 entities in total)
Functional Keywords	factor xa, napc2, selectide, hydrolase-hydrolase inhibitor complex, blood clotting, hydrolase/hydrolase inhibitor
Biological source	Ancylostoma caninum (dog hookworm) More
Cellular location	Secreted: P00742 P00742
Total number of polymer chains	4
Total formula weight	53804.25
Authors	Murakami, M.T.,Geiger, G.,Tulinsky, A.,Arni, R.K. (deposition date: 2006-06-09, release date: 2007-02-13, Last modification date: 2017-10-18)
Primary citation	Murakami, M.T.,Rios-Steiner, J.,Weaver, S.E.,Tulinsky, A.,Geiger, J.H.,Arni, R.K. Intermolecular Interactions and Characterization of the Novel Factor Xa Exosite Involved in Macromolecular Recognition and Inhibition: Crystal Structure of Human Gla-domainless Factor Xa Complexed with the Anticoagulant Protein NAPc2 from the Hematophagous Nematode Ancylostoma caninum. J.Mol.Biol., 366:602-610, 2007 Cited by PubMed: 17173931 DOI: 10.1016/j.jmb.2006.11.040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation