2H77

Crystal structure of human TR alpha bound T3 in monoclinic space group

Summary for 2H77

• Entry DOI: 10.2210/pdb2h77/pdb
• Related: 2H6W 2H79
• Descriptor: THRA protein, 3,5,3'TRIIODOTHYRONINE (3 entities in total)
• Functional Keywords: tr alpha, t3, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q6FH41
• Total number of polymer chains: 1
• Total formula weight: 31629.13

Authors

Nascimento, A.S.,Dias, S.M.G.,Nunes, F.M.,Aparicio, R.,Bleicher, L.,Ambrosio, A.L.B.,Figueira, A.C.M.,Santos, M.A.M.,Neto, M.O.,Fischer, H.,Togashi, H.F.M.,Craievich, A.F.,Garrat, R.C.,Baxter, J.D.,Webb, P.,Polikarpov, I. (deposition date: 2006-06-01, release date: 2006-07-25, Last modification date: 2023-11-15)

• Primary citation: Nascimento, A.S.,Dias, S.M.G.,Nunes, F.M.,Aparicio, R.,Ambrosio, A.L.B.,Bleicher, L.,Figueira, A.C.M.,Santos, M.A.M.,Neto, M.O.,Fischer, H.,Togashi, M.,Craievich, A.F.,Garratt, R.C.,Baxter, J.D.,Webb, P.,Polikarpov, I.; Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.; J.Mol.Biol., 360:586-598, 2006; PubMed: 16781732; DOI: 10.1016/j.jmb.2006.05.008

Experimental method

X-RAY DIFFRACTION (2.33 Å)