2H77
Crystal structure of human TR alpha bound T3 in monoclinic space group
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THRA protein | polymer | 269 | 30978.2 | 1 | UniProt (Q6FH41) Pfam (PF00104) UniProt (by SIFTS) (P10827) | Homo sapiens (human) | |
| 2 | B (A) | 3,5,3'TRIIODOTHYRONINE | non-polymer | 651.0 | 1 | Chemie (T3) | |||
| 3 | C (A) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 148 - 410 (UniProt: Q6FH41)
| PDB | External Database | Details |
|---|---|---|
| Ala 142 | - | cloning artifact |
| Arg 143 | - | cloning artifact |
| Gly 144 | - | cloning artifact |
| Ser 145 | - | cloning artifact |
| His 146 | - | cloning artifact |
| Met 147 | - | cloning artifact |
| Cas 334 | Cys 334 | modified residue |
| Cas 380 | Cys 380 | modified residue |
| Cas 388 | Met 388 | engineered mutation |
| Cas 392 | Cys 392 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30978.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 651.0 | |
| All* | Total formula weight | 31629.1 |
