2H6P
Crystal structure of HLA-B*3501 presenting the human cytochrome P450 derived peptide, KPIVVLHGY
Summary for 2H6P
Entry DOI | 10.2210/pdb2h6p/pdb |
Descriptor | HLA-B35, Beta-2-microglobulin, 9 mer peptide from Cytochrome P450, ... (4 entities in total) |
Functional Keywords | immune system, gene regulation |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P61769 Endoplasmic reticulum membrane; Peripheral membrane protein: P33260 |
Total number of polymer chains | 3 |
Total formula weight | 44715.67 |
Authors | Archbold, J.K.,Macdonald, W.A.,Rossjohn, J. (deposition date: 2006-05-31, release date: 2006-09-19, Last modification date: 2011-07-13) |
Primary citation | Archbold, J.K.,Macdonald, W.A.,Miles, J.J.,Brennan, R.M.,Kjer-Nielsen, L.,McCluskey, J.,Burrows, S.R.,Rossjohn, J. Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry J.Biol.Chem., 281:34324-34332, 2006 Cited by PubMed: 16963442DOI: 10.1074/jbc.M606755200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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