2H67
NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures
Summary for 2H67
Entry DOI | 10.2210/pdb2h67/pdb |
Descriptor | Insulin A chain, Insulin B chain (2 entities in total) |
Functional Keywords | hormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5727.52 |
Authors | |
Primary citation | Hua, Q.X.,Liu, M.,Hu, S.Q.,Jia, W.,Arvan, P.,Weiss, M.A. A Conserved Histidine in Insulin Is Required for the Foldability of Human Proinsulin: Structure and function of an Alab5 analog. J.Biol.Chem., 281:24889-24899, 2006 Cited by PubMed: 16728398DOI: 10.1074/jbc.M602617200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report