2H64

Crystal structure of a ternary ligand-receptor complex of BMP-2

Summary for 2H64

• Entry DOI: 10.2210/pdb2h64/pdb
• Related: 1REU 2H62
• Descriptor: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, Acvr2b protein, ... (4 entities in total)
• Functional Keywords: tgf-beta superfamily, ligand-receptor complex, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P12643; Membrane; Single-pass type I membrane protein: P36894
• Total number of polymer chains: 3
• Total formula weight: 38789.55

Authors

Mueller, T.D.,Sebald, W.,Weber, D. (deposition date: 2006-05-30, release date: 2007-04-10, Last modification date: 2021-10-20)

• Primary citation: Weber, D.,Kotzsch, A.,Nickel, J.,Harth, S.,Seher, A.,Mueller, U.,Sebald, W.,Mueller, T.D.; A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.; Bmc Struct.Biol., 7:6-6, 2007; PubMed: 17295905; DOI: 10.1186/1472-6807-7-6

Experimental method

X-RAY DIFFRACTION (1.92 Å)