2H1L
The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex
Summary for 2H1L
Entry DOI | 10.2210/pdb2h1l/pdb |
Descriptor | Large T antigen, Cellular tumor antigen p53, ZINC ION (3 entities in total) |
Functional Keywords | p53 loop-3 conformation change, viral protein |
Biological source | Simian virus 40 More |
Total number of polymer chains | 24 |
Total formula weight | 786950.16 |
Authors | Lilyestrom, W.,Klein, M.G.,Chen, X.S. (deposition date: 2006-05-16, release date: 2006-09-12, Last modification date: 2023-08-30) |
Primary citation | Lilyestrom, W.,Klein, M.G.,Zhang, R.,Joachimiak, A.,Chen, X.S. Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes Dev., 20:2373-2382, 2006 Cited by PubMed: 16951253DOI: 10.1101/gad.1456306 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.16 Å) |
Structure validation
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