2GZA

Crystal structure of the VirB11 ATPase from the Brucella Suis type IV secretion system in complex with sulphate

Summary for 2GZA

Entry DOI	10.2210/pdb2gza/pdb
Descriptor	Type IV secretion system protein VirB11, SULFATE ION (3 entities in total)
Functional Keywords	secretion, atpase, hydrolase
Biological source	Brucella suis
Cellular location	Cytoplasm : Q8FXK7
Total number of polymer chains	3
Total formula weight	122626.87
Authors	Hare, S.,Bayliss, R.,Baron, C.,Waksman, G. (deposition date: 2006-05-11, release date: 2006-07-11, Last modification date: 2023-08-30)
Primary citation	Hare, S.,Bayliss, R.,Baron, C.,Waksman, G. A Large Domain Swap in the VirB11 ATPase of Brucella suis Leaves the Hexameric Assembly Intact J.Mol.Biol., 360:56-66, 2006 Cited by PubMed Abstract: VirB11 ATPases are hexameric assemblies that power type IV secretion systems in bacteria. The hexamer of Brucella suis VirB11 (BsB11), like that of the Helicobacter pylori VirB11 (Hp0525), consists of a double ring structure formed by the N-terminal and C-terminal domains of each monomer. However, the monomer differs dramatically from that of Hp0525 by a large domain swap that leaves the hexameric assembly intact but profoundly alters the nucleotide-binding site and the interface between subunits. PubMed: 16730027 DOI: 10.1016/j.jmb.2006.04.060 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation