2GYI
DESIGN, SYNTHESIS, AND CHARACTERIZATION OF A POTENT XYLOSE ISOMERASE INHIBITOR, D-THREONOHYDROXAMIC ACID, AND HIGH-RESOLUTION X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE ENZYME-INHIBITOR COMPLEX
Replaces: 1GYISummary for 2GYI
Entry DOI | 10.2210/pdb2gyi/pdb |
Descriptor | XYLOSE ISOMERASE, MAGNESIUM ION, 2,3,4,N-TETRAHYDROXY-BUTYRIMIDIC ACID, ... (4 entities in total) |
Functional Keywords | isomerase(intramolecular oxidoreductase) |
Biological source | Streptomyces olivochromogenes |
Cellular location | Cytoplasm: P15587 |
Total number of polymer chains | 2 |
Total formula weight | 86089.15 |
Authors | Allen, K.N.,Lavie, A.,Petsko, G.A.,Ringe, D. (deposition date: 1994-09-01, release date: 1995-07-10, Last modification date: 2024-02-14) |
Primary citation | Allen, K.N.,Lavie, A.,Petsko, G.A.,Ringe, D. Design, Synthesis, and Characterization of a Potent Xylose Isomerase Inhibitor, D-Threonohydroxamic Acid, and High-Resolution X-Ray Crystallographic Structure of the Enzyme-Inhibitor Complex Biochemistry, 34:3742-3749, 1995 Cited by PubMed: 7893671DOI: 10.1021/bi00011a032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report