2GSG
Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine
Summary for 2GSG
Entry DOI | 10.2210/pdb2gsg/pdb |
Descriptor | monoclonal antibody light chain, monoclonal antibody heavy chain, SULFATE ION, ... (4 entities in total) |
Functional Keywords | fv, monoclonal antibody, poly-glutamine, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 51949.85 |
Authors | Li, P.,Huey-Tubman, K.E.,West Jr., A.P.,Bennett, M.J.,Bjorkman, P.J. (deposition date: 2006-04-26, release date: 2007-04-24, Last modification date: 2011-07-13) |
Primary citation | Li, P.,Huey-Tubman, K.E.,Gao, T.,Li, X.,West Jr., A.P.,Bennett, M.J.,Bjorkman, P.J. The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model. Nat.Struct.Mol.Biol., 14:381-387, 2007 Cited by PubMed: 17450152DOI: 10.1038/nsmb1234 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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