2GRU
Crystal structure of 2-deoxy-scyllo-inosose synthase complexed with carbaglucose-6-phosphate, NAD+ and Co2+
Summary for 2GRU
Entry DOI | 10.2210/pdb2gru/pdb |
Descriptor | 2-deoxy-scyllo-inosose synthase, COBALT (II) ION, SULFITE ION, ... (9 entities in total) |
Functional Keywords | aminoglycoside, 2-deoxystreptamine, dehydroquinate synthase, lyase |
Biological source | Bacillus circulans |
Total number of polymer chains | 2 |
Total formula weight | 83940.13 |
Authors | Nango, E.,Kumasaka, T. (deposition date: 2006-04-25, release date: 2007-05-08, Last modification date: 2023-10-25) |
Primary citation | Nango, E.,Kumasaka, T.,Hirayama, T.,Tanaka, N.,Eguchi, T. Structure of 2-deoxy-scyllo-inosose synthase, a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics, in complex with a mechanism-based inhibitor and NAD+ Proteins, 70:517-527, 2008 Cited by PubMed: 17879343DOI: 10.1002/prot.21526 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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