2GQN

Cystathionine Beta-Lyase (CBL) from Escherichia Coli in complex with N-Hydrazinocarbonylmethyl-2-Nitro-Benzamide

2GQN の概要

• エントリーDOI: 10.2210/pdb2gqn/pdb
• 関連するPDBエントリー: 2FQ6
• 分子名称: Cystathionine beta-lyase, (5-HYDROXY-6-METHYL-4-((2-(2-(2-NITROBENZAMIDO)ACETYL)HYDRAZINYL)METHYL)PYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE (3 entities in total)
• 機能のキーワード: protein-inhibitor complex, plp cofactor covalently bount to blp inhibitor, lyase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P06721
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 91803.94

構造登録者

Summerfield, R.,Junop, M.S. (登録日: 2006-04-21, 公開日: 2007-03-06, 最終更新日: 2024-02-14)

• 主引用文献: Ejim, L.J.,Blanchard, J.E.,Koteva, K.P.,Sumerfield, R.,Elowe, N.H.,Chechetto, J.D.,Brown, E.D.,Junop, M.S.,Wright, G.D.; Inhibitors of Bacterial Cystathionine beta-Lyase: Leads for New Antimicrobial Agents and Probes of Enzyme Structure and Function.; J.Med.Chem., 50:755-764, 2007; PubMed: 17300162; DOI: 10.1021/jm061132r

実験手法

X-RAY DIFFRACTION (1.8 Å)