2GPV

Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen and a SMRT peptide

2GPV の概要

• エントリーDOI: 10.2210/pdb2gpv/pdb
• 関連するPDBエントリー: 2GP7 2GPO 2GPP 2GPU
• 分子名称: Estrogen-related receptor gamma, Nuclear receptor corepressor 2, 4-HYDROXYTAMOXIFEN, ... (4 entities in total)
• 機能のキーワード: estrogen related receptor, err, errg, esrrg, nuclear receptor, steroid receptor, smrt, tamoxifen, transcription
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 166631.32

構造登録者

Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Osband-miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T. (登録日: 2006-04-18, 公開日: 2006-09-26, 最終更新日: 2023-08-30)

• 主引用文献: Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Orband-Miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T.; X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.; J.Biol.Chem., 281:37773-37781, 2006; PubMed: 16990259; DOI: 10.1074/jbc.M608410200

実験手法

X-RAY DIFFRACTION (2.85 Å)