2GPO

Estrogen Related Receptor-gamma ligand binding domain complexed with a synthetic peptide from RIP140

Summary for 2GPO

• Entry DOI: 10.2210/pdb2gpo/pdb
• Related: 2GP7 2GPP 2GPU 2GPV
• Descriptor: Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1 (3 entities in total)
• Functional Keywords: estrogen related receptor, err, errg, esrrg, nuclear receptor, steroid receptor, rip140, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : P62508 P48552
• Total number of polymer chains: 2
• Total formula weight: 28917.66

Authors

Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Osband-miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T. (deposition date: 2006-04-18, release date: 2006-09-26, Last modification date: 2024-02-14)

• Primary citation: Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Orband-Miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T.; X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.; J.Biol.Chem., 281:37773-37781, 2006; PubMed: 16990259; DOI: 10.1074/jbc.M608410200

Experimental method

X-RAY DIFFRACTION (1.95 Å)