2GO4
Crystal structure of Aquifex aeolicus LpxC complexed with TU-514
Summary for 2GO4
| Entry DOI | 10.2210/pdb2go4/pdb |
| Descriptor | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION, CHLORIDE ION, ... (5 entities in total) |
| Functional Keywords | lpxc-inhibitor complex, hydrolase |
| Biological source | Aquifex aeolicus |
| Total number of polymer chains | 2 |
| Total formula weight | 62203.37 |
| Authors | Gennadios, H.A.,Whittington, D.A.,Li, X.,Fierke, C.A.,Christianson, D.W. (deposition date: 2006-04-12, release date: 2006-07-04, Last modification date: 2023-08-30) |
| Primary citation | Gennadios, H.A.,Whittington, D.A.,Li, X.,Fierke, C.A.,Christianson, D.W. Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase Biochemistry, 45:7940-7948, 2006 Cited by PubMed: 16800620DOI: 10.1021/bi060823m PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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