2GM9
Structure of rabbit muscle glycogen phosphorylase in complex with thienopyrrole
Summary for 2GM9
Entry DOI | 10.2210/pdb2gm9/pdb |
Related | 2GJ4 |
Descriptor | Glycogen phosphorylase, muscle form, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 2-CHLORO-N-[(3R)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE, ... (4 entities in total) |
Functional Keywords | glycogen phosphorylase, transferase |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 95859.88 |
Authors | Otterbein, L.R.,Pannifer, A.D.,Tucker, J.,Breed, J.,Oikonomakos, N.G.,Minshull, C.,Rowsell, S.,Pauptit, R.A. (deposition date: 2006-04-06, release date: 2007-02-13, Last modification date: 2024-04-03) |
Primary citation | Whittamore, P.R.,Addie, M.S.,Bennett, S.N.,Birch, A.M.,Butters, M.,Godfrey, L.,Kenny, P.W.,Morley, A.D.,Murray, P.M.,Oikonomakos, N.G.,Otterbein, L.R.,Pannifer, A.D.,Parker, J.S.,Readman, K.,Siedlecki, P.S.,Schofield, P.,Stocker, A.,Taylor, M.J.,Townsend, L.A.,Whalley, D.P.,Whitehouse, J. Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies. Bioorg.Med.Chem.Lett., 16:5567-5571, 2006 Cited by PubMed: 16945526DOI: 10.1016/j.bmcl.2006.08.047 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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