Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) from Helicobacter pylori complexed with Compound 2

Summary for 2GLM

Related2GLL 2glp 2glv
Descriptor(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ... (5 entities in total)
Functional Keywordsfabz complex, lyase
Biological sourceHelicobacter pylori
Cellular locationCytoplasm (By similarity) Q5G940
Total number of polymer chains6
Total molecular weight119206.65
Zhang, L.,Liu, W.,Shen, X.,Jiang, H. (deposition date: 2006-04-05, release date: 2007-03-13, Last modification date: 2011-07-13)
Primary citation
Zhang, L.,Liu, W.,Hu, T.,Du, L.,Luo, C.,Chen, K.,Shen, X.,Jiang, H.
Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
J.Biol.Chem., 283:5370-5379, 2008
PubMed: 18093984 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M705566200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.246160.1%3.6%0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-05