2GJ4

Structure of rabbit muscle glycogen phosphorylase in complex with ligand

2GJ4 の概要

• エントリーDOI: 10.2210/pdb2gj4/pdb
• 分子名称: Glycogen phosphorylase, muscle form, SULFATE ION, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: glycogen phosphorylase, transferase
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 96544.30

構造登録者

Otterbein, L.R.,Pannifer, A.D.,Tucker, J.,Breed, J.,Oikonomakos, N.G.,Rowsell, S.,Pauptit, R.A.,Claire, M. (登録日: 2006-03-30, 公開日: 2007-02-13, 最終更新日: 2024-04-03)

• 主引用文献: Whittamore, P.R.,Addie, M.S.,Bennett, S.N.,Birch, A.M.,Butters, M.,Godfrey, L.,Kenny, P.W.,Morley, A.D.,Murray, P.M.,Oikonomakos, N.G.,Otterbein, L.R.,Pannifer, A.D.,Parker, J.S.,Readman, K.,Siedlecki, P.S.,Schofield, P.,Stocker, A.,Taylor, M.J.,Townsend, L.A.,Whalley, D.P.,Whitehouse, J.; Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies.; Bioorg.Med.Chem.Lett., 16:5567-5571, 2006; PubMed: 16945526; DOI: 10.1016/j.bmcl.2006.08.047

実験手法

X-RAY DIFFRACTION (1.6 Å)