2GAQ
NMR SOLUTION STRUCTURE OF THE FRB DOMAIN OF mTOR
Summary for 2GAQ
Entry DOI | 10.2210/pdb2gaq/pdb |
Related | 1AUE 1FAP 3FAP |
Descriptor | FKBP12-rapamycin complex-associated protein (1 entity in total) |
Functional Keywords | four helical up and down bundle, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P42345 |
Total number of polymer chains | 1 |
Total formula weight | 12101.87 |
Authors | Leone, M.,Pellecchia, M. (deposition date: 2006-03-09, release date: 2006-08-08, Last modification date: 2024-05-29) |
Primary citation | Leone, M.,Crowell, K.J.,Chen, J.,Jung, D.,Chiang, G.G.,Sareth, S.,Abraham, R.T.,Pellecchia, M. The FRB Domain of mTOR: NMR Solution Structure and Inhibitor Design. Biochemistry, 45:10294-10302, 2006 Cited by PubMed: 16922504DOI: 10.1021/bi060976+ PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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