2G97
Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with the Specific Inhibitor FK-866
Summary for 2G97
Entry DOI | 10.2210/pdb2g97/pdb |
Related | 2g95 2g96 |
Descriptor | Nicotinamide phosphoribosyltransferase, (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide (3 entities in total) |
Functional Keywords | visfatin, pbef, namprtase, fk-866, rattus norvegicus, transferase |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Nucleus : Q80Z29 |
Total number of polymer chains | 2 |
Total formula weight | 111808.39 |
Authors | Kim, M.-K.,Eom, S.H. (deposition date: 2006-03-05, release date: 2006-08-01, Last modification date: 2023-10-25) |
Primary citation | Kim, M.-K.,Lee, J.H.,Kim, H.,Park, S.J.,Kim, S.H.,Kang, G.B.,Lee, Y.S.,Kim, J.B.,Kim, K.K.,Suh, S.W.,Eom, S.H. Crystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866 J.Mol.Biol., 362:66-77, 2006 Cited by PubMed: 16901503DOI: 10.1016/j.jmb.2006.06.082 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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