2G25

E. Coli Pyruvate Dehydrogenase Phosphonolactylthiamin Diphosphate Complex

2G25 の概要

• エントリーDOI: 10.2210/pdb2g25/pdb
• 関連するPDBエントリー: 1L8A 1RP7
• 分子名称: Pyruvate dehydrogenase E1 component, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: plthdp, phosphonolactylthiamin diphosphate, pyruvate dehydrogenase e1 component, oxidoreductase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 200964.54

構造登録者

Furey, W.,Arjunan, P.,Chandrasekhar, K. (登録日: 2006-02-15, 公開日: 2006-04-25, 最終更新日: 2023-08-30)

• 主引用文献: Arjunan, P.,Sax, M.,Brunskill, A.,Chandrasekhar, K.,Nemeria, N.,Zhang, S.,Jordan, F.,Furey, W.; A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct.; J.Biol.Chem., 281:15296-15303, 2006; PubMed: 16531404; DOI: 10.1074/jbc.M600656200

実験手法

X-RAY DIFFRACTION (2.1 Å)