2FRA

Human Cathepsin S with CRA-27934, a Nitrile Inhibitor

Summary for 2FRA

• Entry DOI: 10.2210/pdb2fra/pdb
• Descriptor: cathepsin S, N-[1-(AMINOMETHYL)CYCLOPROPYL]-3-(BENZYLSULFONYL)-N~2~-[(1S)-2,2,2-TRIFLUORO-1-(4-HYDROXYPHENYL)ETHYL]-L-ALANINAMIDE (3 entities in total)
• Functional Keywords: papain, cysteine protease, drug design, 27934, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Lysosome: P25774
• Total number of polymer chains: 2
• Total formula weight: 50983.09

Authors

Somoza, J.R. (deposition date: 2006-01-19, release date: 2006-07-25, Last modification date: 2017-10-18)

• Primary citation: Somoza, J.R.; Human Cathepsin S with CRA-27934, a Nitrile Inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)