2FFY
AmpC beta-lactamase N289A mutant in complex with a boronic acid deacylation transition state analog compound SM3
Summary for 2FFY
Entry DOI | 10.2210/pdb2ffy/pdb |
Related | 1PI4 |
Descriptor | Beta-lactamase, POTASSIUM ION, (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, ... (5 entities in total) |
Functional Keywords | ampc; beta-lactamase; deacylation; transition state; boronic acid, hydrolase |
Biological source | Escherichia coli |
Cellular location | Periplasm: P00811 |
Total number of polymer chains | 2 |
Total formula weight | 79813.23 |
Authors | Chen, Y.,Minasov, G.,Roth, T.A.,Prati, F.,Shoichet, B.K. (deposition date: 2005-12-20, release date: 2006-03-28, Last modification date: 2023-08-30) |
Primary citation | Chen, Y.,Minasov, G.,Roth, T.A.,Prati, F.,Shoichet, B.K. The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution J.Am.Chem.Soc., 128:2970-2976, 2006 Cited by PubMed: 16506777DOI: 10.1021/ja056806m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.07 Å) |
Structure validation
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