2FFC

Crystal Structure of Plasmodium Vivax Orotidine-Monophosphate-Decarboxyl UMP Bound

Summary for 2FFC

Descriptororotidine 5-monophosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE (3 entities in total)
Functional Keywordsdecarboxylase, pv-pf10_0225, sgc, structural genomics, structural genomics consortium, lyase
Biological sourcePlasmodium vivax (malaria parasite P. vivax)
Total number of polymer chains1
Total molecular weight40515.78
Authors
Primary citation
Vedadi, M.,Lew, J.,Artz, J.,Amani, M.,Zhao, Y.,Dong, A.,Wasney, G.A.,Gao, M.,Hills, T.,Brokx, S.,Qiu, W.,Sharma, S.,Diassiti, A.,Alam, Z.,Melone, M.,Mulichak, A.,Wernimont, A.,Bray, J.,Loppnau, P.,Plotnikova, O.,Newberry, K.,Sundararajan, E.,Houston, S.,Walker, J.,Tempel, W.,Bochkarev, A.,Kozieradzki, I.,Edwards, A.,Arrowsmith, C.,Roos, D.,Kain, K.,Hui, R.
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151:100-110, 2007
PubMed: 17125854 (PDB entries with the same primary citation)
DOI: 10.1016/j.molbiopara.2006.10.011
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.175602.9%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution