2FF0

Solution Structure of Steroidogenic Factor 1 DNA Binding Domain Bound to its Target Sequence in the Inhibin alpha-subunit Promoter

2FF0 の概要

• エントリーDOI: 10.2210/pdb2ff0/pdb
• 分子名称: GGCTCAGGGCCACAG, CTGTGGCCCTGAGCC, Steroidogenic factor 1, ... (4 entities in total)
• 機能のキーワード: nuclear hormone receptor, protein-dna complex, monomeric receptor-dna complex, hormone-growth factor-dna complex, hormone/growth factor/dna
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Nucleus: P33242
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 21203.72

構造登録者

Little, T.H.,Zhang, Y.,Matulis, C.K.,Weck, J.,Zhang, Z.,Ramachandran, A.,Mayo, K.E.,Radhakrishnan, I. (登録日: 2005-12-17, 公開日: 2006-04-11, 最終更新日: 2022-03-09)

• 主引用文献: Little, T.H.,Zhang, Y.,Matulis, C.K.,Weck, J.,Zhang, Z.,Ramachandran, A.,Mayo, K.E.,Radhakrishnan, I.; Sequence-specific deoxyribonucleic Acid (DNA) recognition by steroidogenic factor 1: a helix at the carboxy terminus of the DNA binding domain is necessary for complex stability.; Mol.Endocrinol., 20:831-843, 2006; PubMed: 16339274; DOI: 10.1210/me.2005-0384

実験手法

SOLUTION NMR