2FEO

Mutant R188M of The Cytidine Monophosphate Kinase from E. coli complexed with dCMP

Summary for 2FEO

• Entry DOI: 10.2210/pdb2feo/pdb
• Related: 2FEM
• Descriptor: Cytidylate kinase, SULFATE ION, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• Functional Keywords: nucleotide monophosphate kinase; transferase, signaling protein, transferase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P0A6I0
• Total number of polymer chains: 1
• Total formula weight: 25155.60

Authors

Ofiteru, A.,Bucurenci, N.,Alexov, E.,Bertrand, T.,Briozzo, P.,Munier-Lehmann, H.,Tourneux, L.,Barzu, O.,Gilles, A.M. (deposition date: 2005-12-16, release date: 2006-01-10, Last modification date: 2024-02-14)

• Primary citation: Ofiteru, A.,Bucurenci, N.,Alexov, E.,Bertrand, T.,Briozzo, P.,Munier-Lehmann, H.,Gilles, A.M.; Structural and functional consequences of single amino acid substitutions in the pyrimidine base binding pocket of Escherichia coli CMP kinase.; Febs J., 274:3363-3373, 2007; PubMed: 17542990; DOI: 10.1111/j.1742-4658.2007.05870.x

Experimental method

X-RAY DIFFRACTION (2.8 Å)