2FEM

Mutant R188M of the Cytidine Monophosphate Kinase From E. Coli

Summary for 2FEM

• Entry DOI: 10.2210/pdb2fem/pdb
• Related: 2FEO
• Descriptor: Cytidylate kinase (1 entity in total)
• Functional Keywords: nucleotide monophosphate kinase; transferase, signaling protein, transferase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P0A6I0
• Total number of polymer chains: 1
• Total formula weight: 24752.34

Authors

Ofiteru, A.,Bucurenci, N.,Alexov, E.,Bertrand, T.,Briozzo, P.,Munier-Lehmann, H.,Tourneux, L.,Barzu, O.,Gilles, A.M. (deposition date: 2005-12-16, release date: 2006-01-10, Last modification date: 2024-02-14)

• Primary citation: Ofiteru, A.,Bucurenci, N.,Alexov, E.,Bertrand, T.,Briozzo, P.,Munier-Lehmann, H.,Gilles, A.M.; Structural and functional consequences of single amino acid substitutions in the pyrimidine base binding pocket of Escherichia coli CMP kinase.; Febs J., 274:3363-3373, 2007; PubMed: 17542990; DOI: 10.1111/j.1742-4658.2007.05870.x

Experimental method

X-RAY DIFFRACTION (1.9 Å)