2FCW

Structure of a Complex Between the Pair of the LDL Receptor Ligand-Binding Modules 3-4 and the Receptor Associated Protein (RAP).

2FCW の概要

• エントリーDOI: 10.2210/pdb2fcw/pdb
• 分子名称: Alpha-2-macroglobulin receptor-associated protein, Low-density lipoprotein receptor, SODIUM ION, ... (6 entities in total)
• 機能のキーワード: protein-protein complex, rap, ldlr, escort protein, calcium-binding, lipid transport-endocytosis-chaperone complex, lipid transport/endocytosis/chaperone
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Endoplasmic reticulum: P30533; Cell membrane; Single-pass type I membrane protein: P01130
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22363.92

構造登録者

Beglova, N.,Fisher, C.,Blacklow, S.C. (登録日: 2005-12-12, 公開日: 2006-05-16, 最終更新日: 2024-04-03)

• 主引用文献: Fisher, C.,Beglova, N.,Blacklow, S.C.; Structure of an LDLR-RAP Complex Reveals a General Mode for Ligand Recognition by Lipoprotein Receptors; Mol.Cell, 22:277-283, 2006; PubMed: 16630895; DOI: 10.1016/j.molcel.2006.02.021

実験手法

X-RAY DIFFRACTION (1.26 Å)