2F8Y

Crystal structure of human Notch1 ankyrin repeats to 1.55A resolution.

2F8Y の概要

• エントリーDOI: 10.2210/pdb2f8y/pdb
• 分子名称: Notch homolog 1, translocation-associated (Drosophila), SULFATE ION (3 entities in total)
• 機能のキーワード: notch, ankyrin repeats, transcription
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein (By similarity). Notch 1 intracellular domain: Nucleus (By similarity): P46531
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49196.82

構造登録者

Nam, Y.,Sliz, P.,Blacklow, S.C. (登録日: 2005-12-04, 公開日: 2006-04-04, 最終更新日: 2023-08-30)

• 主引用文献: Nam, Y.,Sliz, P.,Song, L.,Aster, J.C.,Blacklow, S.C.; Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.; Cell(Cambridge,Mass.), 124:973-983, 2006; PubMed: 16530044; DOI: 10.1016/j.cell.2005.12.037

実験手法

X-RAY DIFFRACTION (1.55 Å)