2F57

Crystal Structure Of The Human P21-Activated Kinase 5

2F57 の概要

• エントリーDOI: 10.2210/pdb2f57/pdb
• 分子名称: Serine/threonine-protein kinase PAK 7, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE, ... (4 entities in total)
• 機能のキーワード: pak5, kinase domains, groupii paks, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion: Q9P286
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73127.64

構造登録者

Eswaran, J.,Turnbull, A.,Ugochukwu, E.,Papagrigoriou, E.,Bray, J.,Das, S.,Savitsky, P.,Smee, C.,Burgess, N.,Fedorov, O.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.,Weigelt, J.,Sundstrom, M.,Edwards, A.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2005-11-25, 公開日: 2005-12-13, 最終更新日: 2023-08-23)

• 主引用文献: Eswaran, J.,Lee, W.H.,Debreczeni, J.E.,Filippakopoulos, P.,Turnbull, A.,Fedorov, O.,Deacon, S.W.,Peterson, J.R.,Knapp, S.; Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs.; Structure, 15:201-213, 2007; PubMed: 17292838; DOI: 10.1016/j.str.2007.01.001

実験手法

X-RAY DIFFRACTION (1.8 Å)