2F2E

Crystal Structure of PA1607, a Putative Transcription Factor

Summary for 2F2E

• Entry DOI: 10.2210/pdb2f2e/pdb
• Descriptor: PA1607, SULFATE ION, alpha-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: transcription factor, helix-trun-helix, apc5613, structural genomics, psi, protein structure initiative, midwest center for structural genomics, mcsg, dna binding protein-structural genomics complex, dna binding protein/structural genomics
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 33310.75

Authors

Sieminska, E.A.,Xu, X.,Zheng, H.,Lunin, V.,Cuff, M.,Joachimiak, A.,Edwards, A.,Savchenko, A.,Sanders, D.A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2005-11-16, release date: 2006-03-14, Last modification date: 2024-10-30)

Primary citation

Sieminska, E.A.,Xu, X.,Savchenko, A.,Sanders, D.A.
The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor.
Protein Sci., 16:543-549, 2007

PubMed Abstract: The structure of the PA1607 protein from Pseudomonas aureginosa was determined at 1.85 A resolution using the Se-Met multiwavelength anomalous diffraction (MAD) technique. PA1607 forms a dimer and adopts a winged-helix motif similar to the MarR family of transcription regulators, though it has an unusual dimerization profile. The DNA-binding regions and a putative metal-binding site are not conserved in PA1607.

PubMed: 17322537
DOI: 10.1110/ps.062668207

Experimental method

X-RAY DIFFRACTION (1.85 Å)