2F1O

Crystal Structure of NQO1 with Dicoumarol

2F1O の概要

• エントリーDOI: 10.2210/pdb2f1o/pdb
• 分子名称: NAD(P)H dehydrogenase [quinone] 1, BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: protein inhibitor, structural genomics, israel structural proteomics center, ispc, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P15559
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 255186.06

構造登録者

Shaul, Y.,Asher, G.,Dym, O.,Tsvetkov, P.,Adler, J.,Israel Structural Proteomics Center (ISPC) (登録日: 2005-11-15, 公開日: 2006-05-16, 最終更新日: 2023-08-23)

• 主引用文献: Asher, G.,Dym, O.,Tsvetkov, P.,Adler, J.,Shaul, Y.; The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.; Biochemistry, 45:6372-6378, 2006; PubMed: 16700548; DOI: 10.1021/bi0600087

実験手法

X-RAY DIFFRACTION (2.75 Å)