2F14
Tne Crystal Structure of the Human Carbonic Anhydrase II in Complex with a Fluorescent Inhibitor
Summary for 2F14
| Entry DOI | 10.2210/pdb2f14/pdb |
| Related | 1CA2 |
| Descriptor | Carbonic anhydrase 2, ZINC ION, 4-(HYDROXYMERCURY)BENZOIC ACID, ... (6 entities in total) |
| Functional Keywords | carbonic anhydrase ii, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 30335.81 |
| Authors | Alterio, V.,Pedone, C.,De Simone, G. (deposition date: 2005-11-14, release date: 2006-10-24, Last modification date: 2023-08-23) |
| Primary citation | Alterio, V.,Vitale, R.M.,Monti, S.M.,Pedone, C.,Scozzafava, A.,Cecchi, A.,De Simone, G.,Supuran, C.T. Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX. J.Am.Chem.Soc., 128:8329-8335, 2006 Cited by PubMed: 16787097DOI: 10.1021/ja061574s PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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