2EZ7

Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII and XIV with L- and D-histidine and crystallographic analysis of their adducts with isoform II: engineering proton transfer processes within the active site of an enzyme

2EZ7 の概要

• エントリーDOI: 10.2210/pdb2ez7/pdb
• 分子名称: Carbonic anhydrase 2, MERCURY (II) ION, ZINC ION, ... (5 entities in total)
• 機能のキーワード: carbonic anhydrase ii, activators, lyase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P00918
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29711.22

構造登録者

Temperini, C.,Scozzafava, A.,Vullo, D.,Supuran, C.T. (登録日: 2005-11-10, 公開日: 2006-07-18, 最終更新日: 2024-02-14)

• 主引用文献: Temperini, C.,Scozzafava, A.,Vullo, D.,Supuran, C.T.; Carbonic Anhydrase Activators. Activation of Isozymes I, II, IV, VA, VII, and XIV with L- and D-Histidine and Crystallographic Analysis of Their Adducts with Isoform II: Engineering Proton-Transfer Processes within the Active Site of an Enzyme.; Chemistry, 12:7057-7066, 2006; PubMed: 16807956; DOI: 10.1002/chem.200600159

実験手法

X-RAY DIFFRACTION (2 Å)