2EV9

Crystal Structure of Shikimate 5-Dehydrogenase (AroE) from Thermus Thermophilus HB8 in complex with NADP(H) and shikimate

Summary for 2EV9

Entry DOI	10.2210/pdb2ev9/pdb
Related	1WXD 2CY0 2D5C
Descriptor	shikimate 5-dehydrogenase, SULFATE ION, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, ... (5 entities in total)
Functional Keywords	substrate, shikimate, cofactor, dimer, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, oxidoreductase
Biological source	Thermus thermophilus
Total number of polymer chains	2
Total formula weight	57917.42
Authors	Bagautdinov, B.,Kunishima, N.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2005-10-31, release date: 2006-05-01, Last modification date: 2023-10-25)
Primary citation	Bagautdinov, B.,Kunishima, N. Crystal Structures of Shikimate Dehydrogenase AroE from Thermus thermophilus HB8 and its Cofactor and Substrate Complexes: Insights into the Enzymatic Mechanism J.Mol.Biol., 373:424-438, 2007 Cited by PubMed: 17825835 DOI: 10.1016/j.jmb.2007.08.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation