2ES0

Structure of the regulator of G-protein signaling domain of RGS6

2ES0 の概要

• エントリーDOI: 10.2210/pdb2es0/pdb
• 分子名称: regulator of G-protein signalling 6 (2 entities in total)
• 機能のキーワード: human rgs6, regulator of g-protein signaling 6, gtpase-activating proteins (gap), domain swap, structural genomics, structural genomics consortium, sgc, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm : P49758
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17236.52

構造登録者

Schoch, G.A.,Phillips, C.,Turnbull, A.,Niesen, F.,Johansson, C.,Elkins, J.M.,Longman, E.,Gilealdi, C.,Sobott, F.,Ball, L.,Sundstrom, M.,Edwards, A.,Arrowsmith, C.,von Delft, F.,Doyle, D.A.,Structural Genomics Consortium (SGC) (登録日: 2005-10-25, 公開日: 2005-11-29, 最終更新日: 2023-08-23)

• 主引用文献: Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.; Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.; Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008; PubMed: 18434541; DOI: 10.1073/pnas.0801508105

実験手法

X-RAY DIFFRACTION (2.1 Å)