2EH8

Crystal structure of the complex of humanized KR127 fab and PRES1 peptide epitope

Summary for 2EH8

• Entry DOI: 10.2210/pdb2eh8/pdb
• Related: 2EH7
• Descriptor: HUMANIZED KR127 FAB, LIGHT CHAIN, HUMANIZED KR127 FAB, HEAVY CHAIN, PreS1/PreS2/surface protein, ... (4 entities in total)
• Functional Keywords: hepatitis b virus, humanized antibody, monoclonal antibody, neutralization, pres1, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 48168.60

Authors

Chi, S.-W.,Kim, S.-J.,Maeng, C.-Y.,Hong, H.J.,Ryu, S.-E. (deposition date: 2007-03-05, release date: 2008-01-15, Last modification date: 2023-10-25)

• Primary citation: Chi, S.-W.,Maeng, C.-Y.,Kim, S.J.,Oh, M.S.,Ryu, C.J.,Kim, S.-J.,Han, K.-H.,Hong, H.J.,Ryu, S.-E.; Broadly neutralizing anti-hepatitis B virus antibody reveals a complementarity determining region H3 lid-opening mechanism; Proc.Natl.Acad.Sci.Usa, 104:9230-9235, 2007; PubMed: 17517649; DOI: 10.1073/pnas.0701279104

Experimental method

X-RAY DIFFRACTION (2.6 Å)