2EGH
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with a magnesium ion, NADPH and fosmidomycin
Summary for 2EGH
Entry DOI | 10.2210/pdb2egh/pdb |
Descriptor | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, MAGNESIUM ION, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, ... (5 entities in total) |
Functional Keywords | protein-inhibitor complex, oxidoreductase |
Biological source | Escherichia coli str. K12 substr. |
Total number of polymer chains | 2 |
Total formula weight | 94253.43 |
Authors | Yajima, S.,Hara, K.,Iino, D.,Sasaki, Y.,Kuzuyama, T.,Seto, H. (deposition date: 2007-03-01, release date: 2007-06-19, Last modification date: 2023-10-25) |
Primary citation | Yajima, S.,Hara, K.,Iino, D.,Sasaki, Y.,Kuzuyama, T.,Ohsawa, K.,Seto, H. Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin Acta Crystallogr.,Sect.F, 63:466-470, 2007 Cited by PubMed: 17554164DOI: 10.1107/S1744309107024475 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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