2EAU

Crystal structure of the SR CA2+-ATPASE with bound CPA in the presence of curcumin

2EAU の概要

• エントリーDOI: 10.2210/pdb2eau/pdb
• 関連するPDBエントリー: 1WPG 2AGV 2EAR 2EAS 2EAT
• 分子名称: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, PHOSPHATIDYLETHANOLAMINE (3 entities in total)
• 機能のキーワード: membrane protein, p-type atpase, had fold, ca2+, ion pump, hydrolase
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• 細胞内の位置: Endoplasmic reticulum membrane; Multi-pass membrane protein: P04191
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 112167.12

構造登録者

Takahashi, M.,Kondou, Y.,Toyoshima, C. (登録日: 2007-02-02, 公開日: 2007-03-27, 最終更新日: 2023-10-25)

• 主引用文献: Takahashi, M.,Kondou, Y.,Toyoshima, C.; Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors; Proc.Natl.Acad.Sci.Usa, 104:5800-5805, 2007; PubMed: 17389383; DOI: 10.1073/pnas.0700979104

実験手法

X-RAY DIFFRACTION (2.8 Å)