2E7F

5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase complexed with methyltetrahydrofolate to 2.2 Angsrom resolution

2E7F の概要

• エントリーDOI: 10.2210/pdb2e7f/pdb
• 関連するPDBエントリー: 1AD4 1AJ0 1F6Y 1Q8J 1TWW 1TX0
• 分子名称: 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, ... (4 entities in total)
• 機能のキーワード: methyltetrahydrofolate-protein complex, corrionoid, vitamin b12, tim barrel, transferase
• 由来する生物種: Moorella thermoacetica
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58275.31

構造登録者

Doukov, T.I.,Drennan, C.L.,Hemmi, H.,Ragsdale, S.W. (登録日: 2007-01-09, 公開日: 2007-01-30, 最終更新日: 2023-10-25)

• 主引用文献: Doukov, T.I.,Hemmi, H.,Drennan, C.L.,Ragsdale, S.W.; Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases.; J.Biol.Chem., 282:6609-6618, 2007; PubMed: 17172470; DOI: 10.1074/jbc.M609828200

実験手法

X-RAY DIFFRACTION (2.2 Å)