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2E6Y

Covalent complex of orotidine 5'-monophosphate decarboxylase (ODCase) with 6-Iodo-UMP

Summary for 2E6Y
Entry DOI10.2210/pdb2e6y/pdb
Related1dv7 1dvj 1kly 1klz 1km0 1km1 1km2 1km3 1km4 1km5 1km6 1lol 1loq 1lor 1los 1lp6 1x1z
DescriptorOrotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE, GLYCEROL, ... (4 entities in total)
Functional Keywordstim-barrel, lyase
Biological sourceMethanothermobacter thermautotrophicus
Total number of polymer chains2
Total formula weight55775.54
Authors
Fujihashi, M.,Bello, A.M.,Kotra, L.P.,Pai, E.F. (deposition date: 2007-01-05, release date: 2007-02-27, Last modification date: 2023-10-25)
Primary citationBello, A.M.,Poduch, E.,Fujihashi, M.,Amani, M.,Li, Y.,Crandall, I.,Hui, R.,Lee, P.I.,Kain, K.C.,Pai, E.F.,Kotra, L.P.
A Potent, Covalent Inhibitor of Orotidine 5'-Monophosphate Decarboxylase with Antimalarial Activity.
J.Med.Chem., 50:915-921, 2007
Cited by
PubMed: 17290979
DOI: 10.1021/jm060827p
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

217705

건을2024-03-27부터공개중

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