2E3K
Crystal structure of the human Brd2 second bromodomain in complexed with the acetylated histone H4 peptide
Summary for 2E3K
Entry DOI | 10.2210/pdb2e3k/pdb |
Related | 2DVV |
Descriptor | Bromodomain-containing protein 2, 15-mer peptide from Histone H4 (3 entities in total) |
Functional Keywords | bromodomain, binds to acetylated histone tails, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (By similarity): P25440 Nucleus: P02309 |
Total number of polymer chains | 6 |
Total formula weight | 55481.63 |
Authors | Padmanabhan, B.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-11-27, release date: 2007-12-11, Last modification date: 2023-11-15) |
Primary citation | Padmanabhan, B.,Umehara, T.,Nakano, K.,Jang, M.K.,Ozato, K.,Yokohama, S. Structural basis for diacetylated histone H4 tail recognition by the second bromodomain of human BRD2 To be Published, |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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