2DYH

Crystal structure of the Keap1 protein in complexed with the N-terminal region of the Nrf2 transcription factor

2DYH の概要

• エントリーDOI: 10.2210/pdb2dyh/pdb
• 関連するPDBエントリー: 1X2J 1X2R
• 分子名称: Kelch-like ECH-associated protein 1, Nrf2/Neh2 peptide from Nuclear factor erythroid 2-related factor 2, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: bet-propeller, kelch motif, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, transcription
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm: Q9Z2X8; Cytoplasm, cytosol: Q60795
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37479.77

構造登録者

Padmanabhan, B.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2006-09-14, 公開日: 2007-09-04, 最終更新日: 2023-10-25)

• 主引用文献: Tong, K.I.,Padmanabhan, B.,Kobayashi, A.,Shang, C.,Hirotsu, Y.,Yokoyama, S.,Yamamoto, M.; Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response; Mol.Cell.Biol., 27:7511-7521, 2007; PubMed: 17785452; DOI: 10.1128/MCB.00753-07

実験手法

X-RAY DIFFRACTION (1.9 Å)