2DQO

Crystal Structure of d(CXCTXCTTC):r(gaagaagag) Where X is 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine

Summary for 2DQO

• Entry DOI: 10.2210/pdb2dqo/pdb
• Related: 2DQP 2DQQ 479D
• Descriptor: DNA (5'-D(*DCP*(OMU)P*DCP*DTP*(OMU)P*DCP*DTP*DTP*DC)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*G)-3'), SODIUM ION, ... (6 entities in total)
• Functional Keywords: modified nucleotide, 5-(n-aminohexyl)carbamoyl-2'-o-methyluridine, a-form rna:dna hybrid duplex, dna-rna hybrid
• Total number of polymer chains: 2
• Total formula weight: 6310.68

Authors

Juan, E.C.M.,Kondo, J.,Ito, T.,Ueno, Y.,Matsuda, A.,Takenaka, A. (deposition date: 2006-05-29, release date: 2007-04-17, Last modification date: 2023-10-25)

• Primary citation: Juan, E.C.M.,Kondo, J.,Kurihara, T.,Ito, T.,Ueno, Y.,Matsuda, A.,Takenaka, A.; Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules; Nucleic Acids Res., 35:1969-1977, 2007; PubMed: 17341465; DOI: 10.1093/nar/gkl821

Experimental method

X-RAY DIFFRACTION (2.3 Å)